Search results for dna damage

“Sulforaphane activates NRF2-regulated cellular defense pathways. In a randomized crossover trial of 60 adults, eating 85 grams of raw watercress daily for eight weeks reduced basal lymphocyte DNA damage by 17% and oxidative purine DNA damage by 23.9%.”

“00:03:44 Dr. Bruce Ames' triage theory. 00:08:45 Dr. Patrick's clinical research on the role of DNA damage in cancer and aging and her data that suggests obese individuals accumulate more DNA damage than lean individuals.”

“Antioxidant enzyme activation A normal byproduct of energy metabolism and exercise is reactive oxygen species. Excess concentrations of reactive oxygen species can promote muscle damage, fatigue, immune dysfunction, DNA damage, and cellular senescence.”

“Clinical symptoms of magnesium deficiency are unlikely, but long term insufficiency can lead to the accumulation of DNA damage over time, which is associated with the diseases of aging. In this clip, Dr. Rhonda Patrick talks about the importance of obtaining adequate magnesium in the diet.”

“A growing body of scientific evidence suggests that both fasting and the body's circadian rhythms are factors in the body's ability to repair DNA damage. Periods without eating can enable the body to rest and clear away damaged cells, which secrete compounds that contribute to inflammation.”

“One hypothesis is that DNA repair enzymes, known as PARP (poly ADP-ribose polymerase), might be using up more NAD+ to fix the accumulated DNA damage that occurs with age. Alternately, the cellular pathway that recycles NAD+ may decline in performance with age.”

“Some types of inflammation are damaging to the body, while others, usually more transient and playing a signaling role, can be beneficial. Chronic inflammation creates reactive oxygen species that damage DNA, cellular proteins, and lipids.”

“Hallmarks it leaves alone — DNA mutations, telomere shortening, senescent cells, accumulated protein aggregates, damaged extracellular matrix, tissue-level architectural damage. These belong more to the "damage repair" side of aging rather than the "information reset" side.”

“Protecting DNA and RNA from cytotoxic stimuli like oxidative stress: Creatine has been shown to protect against mitochondrial DNA damage and mutagenesis from UV radiation. It also shows potential for protecting against RNA damage.”

“TBHQ—harms the immune system. Titanium dioxide—a color additive shown to cause DNA damage. Brominated vegetable oil—a stabilizer used in flavored drinks that can cause neurological harm.”