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“Normalizing the timing of food intake via time-restricted eating may help restore microbiome composition, potentially offsetting the increased disease risk. In this clip, Dr. Eran Elinav describes how the circadian rhythmicity of the microbiome is regulated and how this affects human health.”

“As discussed in Dr. Mattson’s review published in Scientific American, the benefit of vegetables is not to flood cells with antioxidants and eliminate all free radicals (which are important for normal cell signaling), but rather for phytochemicals to trigger the cell's own adaptive responses.”

“Dr. D'Agostino cautions against confusing a Westernized obesogenic high-fat diet with a ketogenic diet. In a well-designed preclinical study, researchers fed mice a cyclic ketogenic diet starting at midlife and observed improved healthspan, cognition, and brain function.”

“Dr. Patrick explains that omega-3 fatty acids may help preserve muscle during periods of immobilization, illness, or injury, while Brady Holmer describes creatine as a practical daily tool for training capacity, strength, and recovery.”

“Prospective human cohorts have reported associations between prenatal BPA measurements and later child behavior, sometimes with sex-specific patterns, but results are inconsistent and residual confounding remains possible.”

“Observational physiology research from his group links more frequent lifelong endurance exercise with higher VO2 max and more favorable cardiovascular function, while stopping short of proving that one exact schedule is uniquely optimal.”

“The findings support working on several modifiable factors together, while leaving open how much each component contributes and whether these changes prevent an eventual Alzheimer's diagnosis.”

“In 25,241 adults who reported no structured exercise, a median of three one- or two-minute vigorous lifestyle bouts per day was associated with 38% to 40% lower all-cause and cancer mortality and 48% to 49% lower cardiovascular mortality.”

“The PROT-AGE Study Group recommends at least 1.0 to 1.2 grams of protein per kilogram of body weight per day for most adults over 65 to help maintain lean mass and physical function. Longitudinal evidence connects higher protein intake with better muscle and frailty outcomes.”

“Ketogenic diets range from the exacting therapeutic diet used to treat epilepsy to a liberalized low-glycemic-index diet that is better suited as a lifestyle diet. These diets are high in fat and low in carbohydrates and can be tracked using an objective biomarker – ketones.”