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“Another study in which 22 year old men who engaged in four weeks of high-intensity interval training three days a week and supplemented with 150 milligrams of resveratrol per day, the lowest dose of the studies mentioned so far, did not promote increases in the men's aerobic or anaerobic capacity, exercise substrate utilization, or muscle fiber-specific adaptations compared to exercise alone.”

“As a prominent researcher and long-term follower of the ketogenic diet, Dr. D'Agostino believes that while someone can survive without fruits and vegetables, this dietary pattern may not be optimal for health.”

“Although alcohol may help us feel calm and ready to sleep, it has surprising effects on REM sleep and maybe our waking behaviors too. In this Aliquot, Dr. Matthew Walker, Tim Ferriss, and I discuss some of the risks and surprising effects of alcohol on human health and behavior.”

“Beyond its role in sexual development, testosterone is important for overall health, influencing mood, energy levels, and even cognitive function. Testosterone is also a highly contested topic, especially in the context of resistance exercise, lifestyle, and managing low testosterone.”

“In Aliquots #131 and #133, leading researcher Dr. Darren Candow and I examined creatine's benefits for muscle quality, physical function, skeletal health, and brain resilience, especially in older adults.”

“In Part I of this three-part Aliquot series, creatine expert Dr. Darren Candow and I examine creatine through the lens of two critical systems—muscle and bone—and unpack how creatine supplementation affects muscle quality, physical function, and even skeletal health, particularly in older adults.”

Dr. Rhonda Patrick discusses nicotinamide riboside, biomarkers, belly fat loss, sex-specific health, curcumin & ashwagandha safety.

“A few examples of genes with common polymorphism discussed are MTHFR and folate, NBPF3 and vitamin B6, FUT2 and vitamin B12, BCMO1 and beta-carotene, FADS2 and omega-3 fatty acids, CYP2R1 and vitamin D, PEMT and choline as well as APOE4 and FOXO3.”

“Time-restricted eating involves consuming meals within a specific daily time window. However, choosing the optimal time frame for that window is influenced by many factors, the most important of which is circadian rhythmicity, which alters our body's metabolic responses to food.”

“The subtypes vary in their causes and manifestation, but the underlying pathological features – the accumulation of amyloid-beta plaques and tau tangles in the brain – are the same. Interestingly, amyloid-beta is both a friend and a foe, serving as a neuroprotectant in some scenarios.”