Q&A
Q&A #58: High-Dose Niacin, NAD+ Boosters, & Cardiovascular Risk
Dr. Rhonda Patrick explores collagen peptides, high-dose niacin and vitamin B6, avoiding nano- and microplastics in her latest Q&A.
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Ranked by shared topics, with one result from each original episode.
Q&A
Dr. Rhonda Patrick explores collagen peptides, high-dose niacin and vitamin B6, avoiding nano- and microplastics in her latest Q&A.
Q&A
Dr. Rhonda Patrick discusses iron imbalances, urolithin A, NAD+ boosters, vitamin K2 and hormone replacement therapy in women.
Q&A
Dr. Rhonda Patrick reviews the evidence for nattokinase, how oat beta-glucans may aid with PFAS excretion, and HRT for APOE4 carriers.
Episode
“In this podcast, we discuss and critically analyze a recent headline-grabbing editorial that was published in the Annals of Internal Medicine that reviewed three studies on the topic of multivitamins and chronic disease prevention. We analyze the important shortcomings of the studies and talk about the mechanism.”
Episode
“The fascinating way Dr. Panda is using human anecdote from his trial to ask new scientific questions he wouldn't think to ask and then going back to animal data to figure it out and how this unique approach forms a sort of closed loop pattern: animal → human feedback → back to animal for mechanism.”
Clip
“Compared with one sauna session per week, four to seven weekly sessions were associated with 66% lower dementia hazard and 65% lower Alzheimer's disease hazard, showing a strong dose-related pattern in this population. A second Finnish cohort followed 13,994 men and women.”
Clip
“In this clip, Dr. Rhonda Patrick distinguishes several sleep exposures. Mild restriction means losing roughly one to three hours for several nights; severe laboratory restriction can mean four hours in bed; chronic cohort studies compare habitual short and long sleep.”
Episode
“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”
Clip
“Prolonged endurance exercise, heavy sweating, sauna use, and a minimally processed diet can also increase the practical need to replace electrolytes, which is different from routinely adding large doses for a sedentary person eating processed foods.”
Clip
“Dr. Patrick builds the strength sessions around compound movements such as squats, deadlifts, and overhead presses, then adds circuit-style exercises. She uses progressive loading, usually stops heavy lifts short of failure, and lets lighter movements move closer to failure when technique remains controlled.”