Related Episodes for Senescence

“The fact that poor sleep is linked with the aggregation of amyloid-beta plaques in the brain and Alzheimer's disease is not surprising. Although some strategies for improving the quality of sleep among people with Alzheimer's have been identified, this might be too late to turn the tide of cognitive decline.”

“In this clip, Dr. Michael Snyder discusses how people age in distinct ways and at varying rates and how knowing our "ageotype" might offer targets for preventing age-related diseases.”

“The stability of DNA methylation patterns - in terms of sample reliability - makes the use of epigenetic clock data an attractive tool in the hands of researchers investigating aging around the world.”

“Young people usually bounce back from muscle loss quite quickly, but for older adults, the stakes are higher, as repeated inactivity can lead to irreversible muscle loss and diminished strength, critically impacting their daily activities.”

“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”

“Rebuilding muscle relies on proper nutrition and exercise, but aging reduces the body's response to both. Extended periods of inactivity, such as post-surgery or during illness, can rapidly deplete muscle mass, especially in older people, potentially pushing them into a "catabolic crisis."”

“In part I of this two-part series on the future of aging research, we discussed the hallmarks of aging and the cutting-edge therapies aimed at understanding and manipulating the complex processes underlying these hallmarks, including epigenetic aging clocks and pluripotent stem cells.”

“A May 2025 Nature paper showed taurine uptake may fuel aggressive myeloid leukemias in laboratory and mouse models, illustrating how nutrients beneficial to healthy tissues may also feed certain cancers.”

“In this Aliquot, Drs. Peter Attia, Stuart Phillips, Morgan Levine, Brad Schoenfeld, Michael Snyder, Valter Longo, Martin Gibala, George Church, as well as Kevin and Darya Rose and myself, share our strategies for finding our fitness.”

“Martin Gibala, Bill Harris, and Peter Attia about three proven ways to promote health and longevity: boosting cardiorespiratory fitness, ensuring you're getting plenty of omega-3 fatty acids, and maintaining healthy blood glucose levels.”