Related Episodes for Urolithin A

“In the prospective Framingham Offspring Study, people in the highest red-blood-cell DHA group had approximately 49 percent lower risk of developing Alzheimer's disease than those in the lowest group.”

“The PROT-AGE Study Group recommends at least 1.0 to 1.2 grams of protein per kilogram of body weight per day for most adults over 65 to help maintain lean mass and physical function. Longitudinal evidence connects higher protein intake with better muscle and frailty outcomes.”

“Observational studies using DXA or CT imaging associate higher alcohol intake with greater visceral fat, with individual responses shaped by dose, drinking pattern, diet, sex, activity, body composition, and metabolic health.”

“A 2025 network meta-analysis of 217 randomized trials and 15,684 people with knee osteoarthritis found that aerobic exercise was likely the most beneficial exercise category for pain, function, gait, and quality of life.”

“In this clip from Dr. Rhonda Patrick's appearance on Next Question with Katie Couric, she explains how sustained exercise can improve cardiovascular fitness and the heart's ability to fill efficiently during middle age.”

“Large treadmill cohorts associate higher measured fitness with lower mortality, while a 46-year study of middle-aged men linked the highest fitness category with about 4.9 additional estimated life-years compared with the lowest category.”

“The 10,000-step target began as a memorable way to market a Japanese pedometer, not as a biological threshold. Walking still matters because replacing sedentary time with movement supports health, and large cohort studies associate more daily steps with lower mortality.”

“Reversing the Cardiac Effects of Sedentary Aging in Middle Age—A Randomized Controlled Trial - In sedentary middle-aged adults, 2 years of regular exercise improved heart function and reduced heart stiffness, potentially lowering future heart failure risk.”

“In the five-year Generation 100 trial, adults ages 70 to 77 completed supervised high-intensity interval training or moderate continuous training, demonstrating that structured vigorous exercise can be feasible in older populations when it is introduced progressively and matched to health and fitness.”

“There's a lot of exciting research right now into aging and maximum lifespan, but scientists have really just scratched the surface of the fascinating topic of how to live longer, healthier lives. Relevant Publications Rootzén, Holger, and Dmitrii Zholud.”