Related Episodes for Aerobic exercise alters tryptophan and kynurenine metabolism (beneficial for depression)

“A systematic review in older adults linked Mediterranean dietary patterns with lower inflammatory markers, while a meta-analysis of randomized trials found that vitamin D supplementation reduced acute respiratory infection risk overall, with the strongest protection among people who were very deficient and received regular doses.”

“During about eight years of follow-up, the models associated one vigorous minute with roughly 4.1 moderate minutes for all-cause mortality, 7.8 minutes for cardiovascular mortality, and 9.4 minutes for type 2 diabetes risk.”

“In this clip from Dr. Rhonda Patrick's appearance on The Diary of a CEO, she explains that a shorter eating window can make calorie reduction easier, while a longer overnight fast shifts fuel use toward fatty acids and ketones.”

“In 15 people with severe traumatic brain injury, sodium lactate infusion increased brain lactate, pyruvate, and glucose without raising intracranial pressure, and a randomized study in 60 patients with mild traumatic brain injury reported better cognitive recovery than hypertonic saline.”

“A meta-analysis of 49 studies involving 1,863 adults found that protein supplementation during prolonged resistance training produced additional gains in one-repetition maximum strength, fat-free mass, and muscle size compared with training alone.”

“In eight young men, seven days of 1,000 milligrams of NR per day changed selected muscle NAD metabolites but did not alter substrate use, mitochondrial respiration, or signaling involved in adaptation to one hour of endurance exercise.”

“In a randomized factorial design, participants were assigned to one gram per day of algae-derived omega-3 or placebo, 2,000 IU of vitamin D3 or placebo, and a 30-minute home strength program three times weekly or a flexibility control.”

“The study she cites did not test a dessert, sugary drink, or habitual added-sugar intake: 74 men completed a standard 75-gram oral glucose tolerance test, after which mean testosterone fell about 25% and remained below baseline at two hours.”

“A separate trial of 153 adults found that smartphone-based mindfulness training combining attention monitoring with acceptance reduced daily loneliness and increased social interactions compared with monitoring alone or an active control.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”