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Related Episodes for Why aging can insidiously mimic short-term immobilization | Dr. Chris McGlory

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How Lactate Links Vigorous Exercise to Brain Health

Jan 7, 2026

“In 15 people with severe traumatic brain injury, sodium lactate infusion increased brain lactate, pyruvate, and glucose without raising intracranial pressure, and a randomized study in 60 patients with mild traumatic brain injury reported better cognitive recovery than hypertonic saline.”

exercise brain mitochondria rhonda
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How Nicotinamide Riboside Relates to Exercise Recovery

Feb 25, 2026

“In eight young men, seven days of 1,000 milligrams of NR per day changed selected muscle NAD metabolites but did not alter substrate use, mitochondrial respiration, or signaling involved in adaptation to one hour of endurance exercise.”

exercise aging metabolism inflammation
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193
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How to Combine Exercise With Compassion Practice

Aug 28, 2026

“A separate trial of 153 adults found that smartphone-based mindfulness training combining attention monitoring with acceptance reduced daily loneliness and increased social interactions compared with monitoring alone or an active control.”

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194
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How Urolithin A Supports Mitochondrial Health

Aug 14, 2026

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

exercise aging performance immune system
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195
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Is there a limit to human longevity?

Jul 20, 2022

“There's a lot of exciting research right now into aging and maximum lifespan, but scientists have really just scratched the surface of the fascinating topic of how to live longer, healthier lives. Relevant Publications Rootzén, Holger, and Dmitrii Zholud.”

aging exercise epigenetics metabolism
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196
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Hyperthermic Conditioning for Hypertrophy, Endurance, and Neurogenesis

Apr 10, 2014

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

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197
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Nutrigenomics, Epigenetics, and Stress Tolerance (IHMC Talk #1)

Nov 8, 2017

“In this talk, we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.”

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Importance of electrolyte supplementation for fasting | Rhonda Patrick

Jul 15, 2019

“Fasting can deplete the body's stores of electrolytes, especially during prolonged fasts or during periods of exercise when electrolytes can be lost during sweat. Because electrolytes are non-calories, replenishment does not appear to alter circadian rhythms.”

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199
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Jim Kean Talks Biomarkers, Building a Spectator Sport

Jul 4, 2015

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

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Ketones may preserve muscle mass during fasting | Dr. Dominic D'Agostino

May 21, 2022

“While ketogenic diets may not be optimal for adding muscle mass, they may be suitable for preserving muscle mass and improving other metabolic parameters, particularly during weight loss and fasting.”

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