Cancer manipulates biologically useful systems to its selfish advantage (dual role of autophagy)
Prolonged fasting stimulates autophagy, an intracellular degradation system involved in the disassembly and recycling of unnecessary or dysfunctional cellular components. Autophagy is thought to be part of a coordinated biological process that is important for exposing cancer cells to the immune system, ultimately leading to their weakening and death. However, the relationship between autophagy and cancer is complicated. In a desperate effort to proliferate, cancer cells may exploit autophagy to obtain the cellular components they require for rapid growth. Autophagy may prevent the survival of pre-malignant cells, but the process can also be hijacked as a malignant adaptation by cancer cells to scavenge resources. In this clip, Dr. Valter Longo discusses how autophagy may function in both normal and cancer cells.
Member support keeps us strong.
If you enjoy the fruits of , you can participate in helping us to keep improving it. Creating a pay-what-you-can subscription does just that! Plus, we throw in occasional member perks and, more importantly, churn out the best possible content without concerning ourselves with the wishes of any dark overlords.
Our website is 100% supported by people like you through this pay-what-you-can mechanism.
Fundamentals$5 / month
Loyal Fan$10 / month
Super Fan$25 / month
Power Supporter$50 / month
Heroic Supporter$125 / month