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Related Episodes for Dosage & supplement factors to consider for resveratrol supplementation | David Sinclair

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How Melatonin and Other Sleep Supplements Compare

Oct 7, 2025

“A meta-analysis of 19 randomized trials involving 1,683 participants found modest average improvements, including about seven minutes less time to fall asleep and eight minutes more total sleep. Product quality can make dose selection difficult.”

nutrition sleep circadian rhythm melatonin
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How Mineral and Chemical Sunscreens Differ in Absorption and Safety

May 24, 2024

“Dr. Patrick's practical takeaway is to favor a well-formulated, non-aerosol mineral sunscreen, especially zinc oxide, while avoiding inhalation and recognizing that mineral and chemical filters have different evidence and uncertainties.”

inflammation rhonda environment skin
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How Oat Beta-Glucan Lowers LDL and May Affect PFAS Levels

Aug 4, 2026

“Randomized trials and a meta-analysis show that at least three grams of oat beta-glucan per day can lower LDL by about five to seven percent, with high-molecular-weight products producing the most consistent effects.”

PFAS beta-glucan gut cholesterol
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How Omega-3 Status Relates to Inflammation, Muscle, and Longevity

Nov 27, 2023

“The excerpt also reviews controlled muscle studies: omega-3 attenuated loss during immobilization and increased the amino-acid-stimulated muscle-protein-synthesis response under tested conditions. These findings do not generalize to every dose or population.”

aging omega-3 inflammation pregnancy
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How Omega-3s Support the Aging Brain

Sep 16, 2026

“In the prospective Framingham Offspring Study, people in the highest red-blood-cell DHA group had approximately 49 percent lower risk of developing Alzheimer's disease than those in the lowest group.”

brain alzheimer's aging omega-3
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How Sulforaphane Activates Cellular Defense Pathways

Dec 29, 2025

“In a 12-week randomized trial of 291 adults living in a region of China with substantial air pollution, a broccoli-sprout beverage increased urinary excretion of a benzene metabolite by 61 percent and an acrolein metabolite by 23 percent.”

cancer dna damage rhonda pollution
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How Sulforaphane Supports Glutathione and Detoxification

Feb 5, 2026

“In a randomized trial of 57 children with autism spectrum disorder, a caregiver-rated secondary behavior scale improved and biomarker changes involved glutathione, mitochondrial, inflammatory, and heat-shock pathways, while the primary clinical outcome was similar between groups.”

rhonda autism pollution sulforaphane
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How to Improve Sleep Continuity and Depth

Sep 3, 2025

“In this FoundMyFitness Premium Q&A preview, Dr. Rhonda Patrick reviews common contributors to fragmented sleep, including insomnia, sleep apnea, nocturia, psychological stress, irregular schedules, caffeine, alcohol, light, noise, temperature, and late eating.”

sleep circadian rhythm melatonin magnesium
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129
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Is there a limit to human longevity?

Jul 20, 2022

“There's a lot of exciting research right now into aging and maximum lifespan, but scientists have really just scratched the surface of the fascinating topic of how to live longer, healthier lives. Relevant Publications Rootzén, Holger, and Dmitrii Zholud.”

aging exercise epigenetics metabolism
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What Collagen Supplements Can and Cannot Do

Aug 12, 2024

“Dr. van Loon sees useful research questions in skin, joints, and recovery after orthopedic surgery, but he keeps those possibilities separate from established muscle-building effects.”

supplements tissue repair skin arthritis
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