Related Episodes for Environmental and genetic causes of Parkinson's disease | Giselle Petzinger

“Altering those cues from those normal day-night patterns can have negative effects on our metabolism, especially in organs like the liver. In this clip, Dr. Satchin Panda describes CLOCK's varied response to light and food and how those responses affect metabolism.”

“Her practical message is to reduce the frequency and size of large glucose exposures. Foods with intact fiber, protein, and minimally processed carbohydrates digest more slowly than refined added sugar, while regular exercise gives skeletal muscle a large destination for circulating glucose.”

“Genetic factors can impact plasma lipoprotein levels and the risk of coronary artery disease. Genes associated with elevated low-density lipoprotein (LDL) cholesterol levels have also been associated with increased heart disease risk, suggesting a causal relationship.”

“In this clip from Dr. Rhonda Patrick's appearance on Modern Wisdom, she explains how a large post-meal glucose rise and fall can contribute to the sluggish feeling people call brain fog. Food order offers one practical lever.”

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”

“For example, growing up in an overly hygienic environment increases a child's risk for developing autoimmune diseases, but exposure to dirt, especially from soil, pets, and roaches, in the first year of life may provide protection against asthma and allergy-related skin disease.”

“A smaller comparative study found improved hair density, shaft size, and anagen-follicle proportion with 2 percent ketoconazole shampoo, while its authors called for larger controlled studies. These results support individualized combinations rather than one universal protocol.”

“Dr. Mattson contends that unstressed cells become complacent, making them more vulnerable to the stressors that cause disease, including oxidative stress and inflammation. In modern times, fasting and exercise are behaviors that mildly stress cells.”

“These events are recapitulated in both exercise and sauna, providing a potential explanation for the sleep-inducing effects of the two activities. In this clip, Dr. Matthew Walker explains how sleep and sauna may induce sleep through their short-term pro-inflammatory effects.”

“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”