Related Episodes for Does the epigenetic clock play a causal role in aging? | Steve Horvath

“I am simply choosing not to blend them into my blueberry smoothie when the goal is to maximize polyphenol exposure.".(https://www.foundmyfitness.com/episodes/blueberry-solocast)'] A 2023 banana-smoothie study caught Rhonda's attention because the effect was unusually large and the mechanism made biological sense.”

“Dr. D'Agostino cautions against confusing a Westernized obesogenic high-fat diet with a ketogenic diet. In a well-designed preclinical study, researchers fed mice a cyclic ketogenic diet starting at midlife and observed improved healthspan, cognition, and brain function.”

“For people concerned about LDL cholesterol, paper-filtered or instant coffee offers a practical way to retain many coffee polyphenols while reducing diterpene exposure. The machine and container also matter.”

“Antibiotic therapy is commonly used to eradicate the bacterium, but sulforaphane, an isothiocyanate compound derived from broccoli, has been shown to reduce H. pylori populations markedly, and may offer a more cost-effective means of treating H.”

“In this video Dr. Rhonda Patrick interviews Dr. Bruce Ames about his triage theory, which he proposes that the body has developed a rationing response to shortages of micronutrients (vitamins and minerals) throughout evolution.”

“Caloric restriction mimetics – compounds that “trick” cells into inducing autophagy even in the setting of sufficient nutrient levels – include resveratrol, which is found in red wine, and spermidine, which is found in cheese.”

“Animal models demonstrate that intermittent fasting is generally beneficial for maintaining muscle mass, but in some disease states, such as ALS, or Lou Gehrig's disease, it can be detrimental.”

“Brady Holmer turns the protocol into a weekly framework: one interval session, one longer easy session, additional base-pace activity, active recovery, and at least two resistance sessions. Dr. Patrick emphasizes the progressive build.”

“Even though the primary endpoints failed (NR did not improve insulin sensitivity or weight loss), he notes a meaningful signal in reduced liver fat—a 2% decrease in the NR group compared to a 0.2% reduction in the placebo group, a difference that didn't reach statistical significance, likely because subjects weren't randomized by liver fat and variability was high.”

“The oversimplified view that high-density lipoprotein (HDL) cholesterol is good, and low-density lipoprotein (LDL) cholesterol is bad has led to misunderstandings of the relationship between cholesterol and cardiovascular disease risk.”