Related Episodes for The evolutionary advantage to depression (and sickness behavior) | Charles Raison

“In this clip from his FoundMyFitness interview with Dr. Rhonda Patrick, Dr. Andy Galpin explains why glutamine becomes conditionally important when training load, energy restriction, illness, or injury increases demand.”

“For people seeking better-supported ways to improve inflammatory health, she points to regular exercise, marine omega-3 intake, and sulforaphane-rich foods as practical areas with a larger human evidence base.”

“Fiber plays a pivotal role in fueling good bacteria in the gut, which produce compounds that keep the immune system in check and prevent autoimmune responses. Research suggests that maintaining a protective mucin layer in the gut helps restrict the release of endotoxin from intestinal bacteria, a major source of inflammation.”

“Translating sleep insights into practical steps These findings highlight the possibility of using heat therapy or vigorous exercise to influence slow-wave sleep, drawing on the interplay between body temperature regulation, immunity, physical activity, and hormones.”

“A meta-analysis of 25 prospective studies associated each additional 10 grams of daily fiber with about a 10 percent lower risk of colorectal cancer, with especially consistent findings for cereal fiber and whole grains.”

“Visceral fat can respond to changes in energy balance and physical activity. A meta-analysis of 40 randomized trials and 2,190 adults with overweight or obesity found that both exercise and calorie restriction reduced CT- or MRI-measured visceral fat.”

“A systematic review in older adults linked Mediterranean dietary patterns with lower inflammatory markers, while a meta-analysis of randomized trials found that vitamin D supplementation reduced acute respiratory infection risk overall, with the strongest protection among people who were very deficient and received regular doses.”

“In an early randomized workplace study, healthy employees who completed an eight-week mindfulness program showed a greater rise in antibodies after influenza vaccination than a waitlist group.”

“Dr. Patrick's practical takeaway is to favor a well-formulated, non-aerosol mineral sunscreen, especially zinc oxide, while avoiding inhalation and recognizing that mineral and chemical filters have different evidence and uncertainties.”

“In eight young men, seven days of 1,000 milligrams of NR per day changed selected muscle NAD metabolites but did not alter substrate use, mitochondrial respiration, or signaling involved in adaptation to one hour of endurance exercise.”