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Related Episodes for How the body produces glucose via gluconeogenesis during ketosis | Dominic D'Agostino

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How Glucose and Added Sugar Relate to Testosterone and Reward Signaling

Mar 25, 2025

“The study she cites did not test a dessert, sugary drink, or habitual added-sugar intake: 74 men completed a standard 75-gram oral glucose tolerance test, after which mean testosterone fell about 25% and remained below baseline at two hours.”

testosterone brain sugar dopamine
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How Urolithin A Supports Mitochondrial Health

Aug 14, 2026

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

exercise aging performance immune system
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103
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How Vigorous Exercise Builds VO2 Max and Heart Flexibility

Jan 2, 2026

“Large treadmill cohorts associate higher measured fitness with lower mortality, while a 46-year study of middle-aged men linked the highest fitness category with about 4.9 additional estimated life-years compared with the lowest category.”

exercise aging performance heart disease
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104
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How Vigorous Exercise Compares With Zone 2

Oct 27, 2025

“For all-cause mortality, the researchers estimated that one minute of vigorous activity was associated with a risk reduction similar to 4.1 minutes of moderate activity or 53.2 minutes of light activity. The estimated differences were larger for some specific outcomes.”

exercise performance diabetes rhonda
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105
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How Vigorous Exercise Improves VO2 Max and Heart Function

Sep 8, 2025

“In this clip from Dr. Rhonda Patrick's appearance on The Tim Ferriss Show, she describes VO2 max as a practical measure of cardiorespiratory fitness and explains why vigorous intervals can create a stronger cardiovascular training stimulus.”

exercise aging performance rhonda
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106
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How Vigorous Exercise Reverses Cardiac Aging

Nov 7, 2025

“A separate 46-year study of 5,107 middle-aged men linked each 1 milliliter per kilogram per minute increase in estimated VO2 max with about 45 additional days of life expectancy. High-intensity intervals are one practical way to improve VO2 max.”

exercise performance heart disease rhonda
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107
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Is there a limit to human longevity?

Jul 20, 2022

“There's a lot of exciting research right now into aging and maximum lifespan, but scientists have really just scratched the surface of the fascinating topic of how to live longer, healthier lives. Relevant Publications Rootzén, Holger, and Dmitrii Zholud.”

aging exercise epigenetics metabolism
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108
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Hyperthermic Conditioning for Hypertrophy, Endurance, and Neurogenesis

Apr 10, 2014

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

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109
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How Vitamin D, Omega-3s, & Exercise May Increase Longevity | Dr. Rhonda Patrick

Nov 9, 2023

“Dr. Patrick describes strategies you can apply immediately to enhance cellular health, protect the nervous system, elevate mood, reduce inflammation, promote muscle and bone function, and help prevent chronic disease.”

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110
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Nutrigenomics, Epigenetics, and Stress Tolerance (IHMC Talk #1)

Nov 8, 2017

“In this talk, we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.”

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