Related Episodes for How Creatine Dose Shapes Muscle and Brain Benefits

“In a small randomized trial of adults aged 60 to 80, five grams per day during 12 weeks of supervised resistance training increased lean mass more than placebo plus training; measured strength and bone outcomes did not significantly differ between groups.”

“A meta-analysis in older adults found greater gains in lean mass and strength when creatine accompanied training, while a systematic review found the most consistent benefits after at least 12 weeks of combined use. Dr. Phillips also highlights emerging cognitive evidence.”

“A meta-analysis restricted to direct regional measures from MRI, CT, or ultrasound found a very small average hypertrophy benefit when creatine was combined with resistance training, with uncertainty around the pooled estimate and variation across sites and populations.”

“In one randomized crossover study of 15 healthy adults, a single dose of 0.35 grams per kilogram changed brain-energy measures and partially reduced deterioration on selected cognitive tasks during 21 hours without sleep.”

“Dr. Brooks's exact practice of waking 96 minutes before dawn comes from the Vedic concept of Brahma Muhurta rather than a tested clinical protocol. Creatine may provide modest cognitive benefits in some settings, although results in healthy adults are mixed.”

“Jet lag often shows up as fatigue after a long flight, reflecting a mismatch between your internal clock and the external world. In this Aliquot, joined by Drs. Michael Grandner and Darren Candow, I explain how jet lag works, which signals are most important for resetting your clock, and how to reduce jet lag before travel and recover more quickly after arrival.”

“In part one of this two-part Aliquot, Dr. Stuart Phillips and I talk about the role of nutrients and supplements in promoting muscle protein synthesis and subsequent increases in muscle mass and strength.”

“Dr. Patrick explains that omega-3 fatty acids may help preserve muscle during periods of immobilization, illness, or injury, while Brady Holmer describes creatine as a practical daily tool for training capacity, strength, and recovery.”

“Dr. Patrick explains that she uses zinc lozenges only during exposure or the earliest signs of illness, often totaling roughly 80 to 100 milligrams per day for a short period. Small randomized zinc-acetate lozenge trials have produced mixed results, with one reporting a shorter cold and another finding no faster recovery with more adverse effects.”

“In a two-year trial of 237 postmenopausal women, approximately 9 to 10 grams per day combined with resistance training and walking did not add a bone-density benefit, so its role is better framed around muscle and physical function.”