Ranked by shared topics, with one result from each original episode.
“Shift work creates a chronic disruption of circadian rhythms that affects sleep, metabolism, decision-making, and long-term health, often in ways people don't recognize until years later. In this Aliquot, joined by Drs.”
“These changes increase infection risk, weaken vaccine responses, and reduce early cancer surveillance. Yet immune aging is not fixed. Movement, sleep, stress regulation, temperature exposure, and nutrition shape immune cell balance and inflammatory activity over time.”
“In this Aliquot, I explain why visceral fat behaves so differently from other fat, how it drives insulin resistance and chronic disease, and what research shows about the most effective ways to reduce it.”
“Coffee consumption is associated with protection from several chronic diseases. Coffee's beneficial effects may stem from its ability to induce autophagy; however, other evidence points to the benefits of caffeine, which can reset the body's internal clocks in the morning.”
“Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu.”
“The decline of deep sleep begins early in life, nearly disappears by age 80, increasing the risk for Alzheimer's disease. These Aliquot segments feature Dr. Charles Raison, a professor of psychiatry, and Dr. Matthew Walker, a professor of neuroscience and psychology.”
“Having a healthy, robust immune system is crucial for our survival. Critical players in the body's antiviral immune response are interferons. Certain lifestyle behaviors can boost interferon production and immune function, including sleep, vitamin D, and hot hydrotherapy.”
“Scientists have also identified interesting links between depression and obesity – likely mediated by elevated inflammation, since fat cells produce a wide array of inflammatory factors. In this Aliquot segment, psychiatrist Dr. Charles Raison describes the links between inflammation and depression.”
“Eating a typical Western diet – high in processed foods and sugar-sweetened beverages – raises blood glucose and insulin levels, promotes inflammation, and contributes to many neurological disorders, including Alzheimer's disease.”
“These changes drive processes that improve cellular respiration, reduce inflammation, enhance memory, and provide protection from cancer – critical aspects in slowing the effects of aging and promoting longevity. Part II of this three-part Aliquot features Dr. Dominic D'Agostino, an expert in ketosis; Dr. Eric Verdin, an expert in aging; and Dr. Valter Longo, an expert in gerontology.”