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Why AI Could Add Decades to Your Lifespan | Dr. Derya Unutmaz

Jul 22, 2026

“Tools, companies, and resources mentioned OpenAI - AI research and deployment company behind widely used GPT systems and developer tools; its science case study describes GPT-5 helping Unutmaz's lab resolve a long-standing immunology question.”

technology genetic engineering diagnostics aging
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How Elevated Blood Sugar Affects the Brain and Heart

Apr 4, 2025

“Her practical message is to reduce the frequency and size of large glucose exposures. Foods with intact fiber, protein, and minimally processed carbohydrates digest more slowly than refined added sugar, while regular exercise gives skeletal muscle a large destination for circulating glucose.”

sugar brain aging inflammation
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93
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Episode

Epigenetic Aging: How old is your DNA?

Dec 11, 2020

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”

epigenetics aging biomarkers genetic engineering
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A diminished interferon response drives poor outcomes in COVID-19 | Roger Seheult

Mar 10, 2021

“Recent studies have identified a connection between an impaired interferon response and severe COVID-19 disease. Strategies that increase the body's core temperature – analogous to having a fever – may be beneficial early in COVID-19 illness.”

covid-19 vitamin d immune system protein
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Exercise and Nutrition Strategies That Support Bone Density After 65

Mar 13, 2026

“In a two-year trial of 237 postmenopausal women, approximately 9 to 10 grams per day combined with resistance training and walking did not add a bone-density benefit, so its role is better framed around muscle and physical function.”

menopause vitamin d exercise aging
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Why VO2 Max Is a Powerful Longevity Marker

Mar 12, 2024

“In this excerpt from Dr. Rhonda Patrick's A4M LongevityFest 2023 keynote, she argues that vigorous exercise is one of the most powerful tools for healthy aging because it can raise cardiorespiratory fitness.”

exercise aging performance mortality
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How Exercise Can Reverse Age-Related Heart Stiffness

Aug 1, 2025

“In 27 men with metabolic syndrome, four four-minute intervals near 90 percent of peak heart rate improved VO2 max more than work-matched moderate exercise. A two-year randomized trial used a broader progressive program in healthy, sedentary adults around age 53.”

exercise aging performance aerobic
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How Vigorous Exercise and Lactate Support Brain Health

Jun 23, 2025

“Controlled human studies support acute brain-related responses to high-intensity exercise. Six short all-out cycling intervals improved selected learning and executive measures while increasing circulating BDNF, IGF-1, and VEGF; lactate tracked several of these changes.”

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Eating to extend healthspan: overnutrition vs undernutrition | Ray Cronise

Feb 28, 2020

“Studies of centenarians suggest that lower levels of inflammation are associated with longevity. Different types of fiber provide fuel to diverse species of bacteria in the gut, which then synthesize byproducts that regulate the inflammatory process.”

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Why VO2 Max Is a Powerful Marker of Longevity

Apr 19, 2024

“Dr. Patrick recommends vigorous intervals when moderate training does not improve an individual’s VO2 max and presents repeated one-minute efforts and the Norwegian 4-by-4 as practical options.”

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