Related Episodes for How Vitamin D Status Connects to Gene, Brain, and Immune Function

“In a six-month trial of adults with peripheral artery disease, a flavanol-rich cocoa beverage improved six-minute walking distance measured 2.5 hours after dosing. In older adults with mild cognitive impairment, higher-flavanol cocoa improved selected verbal-fluency and executive-function tests over eight weeks.”

“However, the term "fasting" can comprise a variety of subtypes. Intermittent fasting, a term lacking specificity, usually refers to interventions such as alternate-day fasting, fasting one day per week, or a five:two eating pattern (fasting for two days per week).”

“The majority of glutamine administered orally is taken up by the liver and gut, with little ending up in the bloodstream. Dr. D'Agostino discourages supplementing with glutamine for patients with cancers of the gastrointestinal tract and even recommends they avoid high glutamine containing foods.”

“The most compelling human signal appears when the brain is under acute strain. In a randomized crossover study, a single dose of 0.35 grams per kilogram during 21 hours of sleep deprivation changed cerebral energy metabolites and preserved selected measures of cognitive performance.”

“A recent meta-analysis also found small benefits in selected cognitive domains, including memory and processing speed, with responses that may depend on age, diet, baseline stores, stress, dose, and the cognitive test used.”

“Tools, companies, and resources mentioned OpenAI - AI research and deployment company behind widely used GPT systems and developer tools; its science case study describes GPT-5 helping Unutmaz's lab resolve a long-standing immunology question.”

“Dr. Cronise describes his extended, unsupplemented fast after which he observed no apparent metabolic changes, and he challenges the paradigm that nutrients need to be balanced daily. In this clip, Dr. Ray Cronise and Dr. Rhonda Patrick discuss the importance of diet in maximizing healthspan and longevity.”

“Dr. Patrick explains that she uses zinc lozenges only during exposure or the earliest signs of illness, often totaling roughly 80 to 100 milligrams per day for a short period. Small randomized zinc-acetate lozenge trials have produced mixed results, with one reporting a shorter cold and another finding no faster recovery with more adverse effects.”

“Her practical message is to reduce the frequency and size of large glucose exposures. Foods with intact fiber, protein, and minimally processed carbohydrates digest more slowly than refined added sugar, while regular exercise gives skeletal muscle a large destination for circulating glucose.”

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”