Related Episodes for Nicotinamide riboside for prevention of hearing loss and the importance of NAD+ for mitochondria | Eric Verdin

“The immune system has strategies for filtering these autoimmune cells out of circulation; however, this filter can malfunction due to age, genetic predisposition, disruption of the gut barrier and gut microbiota, or other environmental exposures.”

“But implementing a ketogenic diet is challenging. In this Aliquot, Dr. Dominic D'Agostino explains how to avoid side effects on a ketogenic diet, provides valuable pointers for success, and explains how the diet might help preserve muscle mass.”

“However, combining fasting with resistance training can stimulate muscle growth. In this Aliquot, Dr. Rhonda Patrick discusses time-restricted eating, fasting, and muscle preservation, highlighting key differences and offering recommendations for specific groups.”

“Time-restricted eating involves consuming meals within a specific daily time window. However, choosing the optimal time frame for that window is influenced by many factors, the most important of which is circadian rhythmicity, which alters our body's metabolic responses to food.”

“While sanitation and clean drinking water are critical to survival, the over sterilization of our environment may play a role in modulating the human immune system. In this clip, Dr. Charles Raison highlights how ancient practices such as heat exposure, long-distance running, and fasting may promote well-being in the modern world.”

“Researchers in Dr. D'Agostino's laboratory observed a decreased tumor burden and enhanced survival in animals that were provided a ketone supplement, even if they were fed a high-carbohydrate diet.”

“Circadian rhythms modulate a wide array of physiological processes, including the body’s production of hormones that regulate sleep, hunger, metabolism, and others, ultimately influencing body weight, performance, and susceptibility to disease.”

“Although some evidence suggests that black, caffeinated coffee or tea may have little effect on the beneficial effects associated with time-restricted eating, experts in the field of circadian biology suggest a more conservative approach that permits coffee and tea only during the designated window of eating.”

“Lunch varied among sardines, mackerel, wild salmon, avocado, nuts, fruit, cheese, and quinoa salad, giving her flexible sources of protein, marine fats, fiber, and fermented foods. Dinner typically paired fish, chicken, or occasional beef with vegetables or salad.”

“Mouse studies of feeding during infection also found different responses across bacterial and viral models, so a minimally processed dietary pattern, regular exercise, and normal hydration and nutrition during illness provide a more useful foundation than one universal food or fasting rule.”