Related Episodes for Resveratrol’s impact on the cardiovascular system | David Sinclair

“In a crossover study of 15 healthy adults, a single 0.35-gram-per-kilogram dose during acute sleep deprivation changed brain-energy metabolites and improved selected cognitive tasks.”

“Cholesterol-lowering drugs can act at several points in the body's handling of lipoproteins. Dr. Rhonda Patrick compares PCSK9 inhibitors, bempedoic acid, and ezetimibe, focusing on how they reduce circulating LDL and apoB-containing particles.”

“The excerpt also reviews controlled muscle studies: omega-3 attenuated loss during immobilization and increased the amino-acid-stimulated muscle-protein-synthesis response under tested conditions. These findings do not generalize to every dose or population.”

“In the prospective Framingham Offspring Study, people in the highest red-blood-cell DHA group had approximately 49 percent lower risk of developing Alzheimer's disease than those in the lowest group.”

“The PROT-AGE Study Group recommends at least 1.0 to 1.2 grams of protein per kilogram of body weight per day for most adults over 65 to help maintain lean mass and physical function. Longitudinal evidence connects higher protein intake with better muscle and frailty outcomes.”

“The Endocrine Society recommends aiming for testosterone concentrations in the mid-normal range while choosing an approved formulation based on patient preference, pharmacokinetics, formulation-specific effects, treatment burden, and cost.”

The video serves as a companion to our 15-page Sprouting Guide (https://www.foundmyfitness.com/sprouting) + Q&A with Dr. Jed Fahey (https://www.foundmyfitness.com/episodes/jed-fahey-q-a) – an illustrated manual to the basics of sprouting that includes a brief summary of the science of sulforaphane plus insights from one of the top researchers in the field of chemoprotection.

“A 2025 network meta-analysis of 217 randomized trials and 15,684 people with knee osteoarthritis found that aerobic exercise was likely the most beneficial exercise category for pain, function, gait, and quality of life.”

“Research in trained cyclists found that daily heart rate variability tracked training load and perceived exertion during an overload period, then returned toward baseline during recovery, supporting its use as a sensitive signal when interpreted against an individual's normal range.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”