Related Episodes for How Time-Restricted Eating affects leaky gut and systemic inflammation | Satchin Panda

“In the prospective Framingham Offspring Study, people in the highest red-blood-cell DHA group had approximately 49 percent lower risk of developing Alzheimer's disease than those in the lowest group.”

“Among 2,315 middle-aged men followed for a median of 20.7 years, using a sauna four to seven times per week was associated with lower sudden cardiac death, cardiovascular mortality, and all-cause mortality than using one weekly session.”

“A 2025 network meta-analysis of 217 randomized trials and 15,684 people with knee osteoarthritis found that aerobic exercise was likely the most beneficial exercise category for pain, function, gait, and quality of life.”

“There's a lot of exciting research right now into aging and maximum lifespan, but scientists have really just scratched the surface of the fascinating topic of how to live longer, healthier lives. Relevant Publications Rootzén, Holger, and Dmitrii Zholud.”

“More than 200 HMOs have been identified, and they are the third most abundant factor in breast milk after fat and lactose. The primary role of HMOs is to serve as prebiotics – compounds that induce the growth or activity of beneficial bacteria.”

“Some of the more unique components of breastmilk are human milk oligosaccharides, or HMOs – complex, indigestible sugars that serve no nutritional purpose. Rather, the primary role of HMOs is to serve as prebiotics to induce the growth or activity of beneficial bacteria in the infant gut.”

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

“While it’s likely that there may be more going on with depression than just inflammation by itself, it could be an incredibly useful lens through which to look at promising avenues to potentially treat or prevent it, since controlling systemic inflammation shows promise as being both important for longevity and health in general.”

“While this system might have served an important function evolutionarily, today it contributes to the chronic inflammation associated with heart disease. In this clip, Dr. Ronald Krauss discusses the role of inflammation in lipoprotein metabolism.”

“Circulating LPS can also bind to lipoproteins, facilitating their absorption in the liver during LDL recycling, effectively removing LPS from circulation and lowering systemic inflammation – a phenomenon demonstrated mechanistically with statins that increase lipoprotein recycling by increasing LDL receptors.”