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Related Episodes for The unique effects of multi-day prolonged fasts (requires more than 48 hours) - Valter Longo

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How Exercise and Sleep Affect Visceral Fat

Jul 1, 2026

“Visceral fat can respond to changes in energy balance and physical activity. A meta-analysis of 40 randomized trials and 2,190 adults with overweight or obesity found that both exercise and calorie restriction reduced CT- or MRI-measured visceral fat.”

exercise obesity sleep inflammation
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How Exercise and Sleep Support Immune Function With Age

Oct 29, 2025

“A systematic review in older adults linked Mediterranean dietary patterns with lower inflammatory markers, while a meta-analysis of randomized trials found that vitamin D supplementation reduced acute respiratory infection risk overall, with the strongest protection among people who were very deficient and received regular doses.”

nutrition exercise aging sleep
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How Aerobic Exercise Supports Hippocampal Growth and Memory

Mar 27, 2025

“She uses that result to make consistency practical. Aerobic exercise does not need to be all-out every day, but sessions that raise heart rate and improve cardiorespiratory fitness provide a meaningful brain stimulus.”

exercise brain bdnf cognition
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How Exercise Intensity Relates to Longevity

Jul 29, 2026

“During about eight years of follow-up, the models associated one vigorous minute with roughly 4.1 moderate minutes for all-cause mortality, 7.8 minutes for cardiovascular mortality, and 9.4 minutes for type 2 diabetes risk.”

exercise obesity diabetes muscle
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How High-Intensity Exercise Improves VO2 Max and Heart Function

Oct 21, 2025

“Longer high-intensity intervals can raise VO2 max efficiently. In a randomized study of 40 healthy, moderately trained men, eight weeks of four four-minute intervals at 90 to 95 percent of maximum heart rate increased VO2 max by 7.2 percent.”

exercise aging performance heart disease
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How High-Intensity Intervals Improve VO2 Max

Jan 28, 2026

“In 5,107 middle-aged men followed for 46 years, moving from very low fitness into progressively higher categories was associated with roughly two to five additional years of life, and each one-unit increase in VO2 max was associated with 45 more days of longevity.”

exercise aging performance heart disease
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How Ketosis Changes Brain Fuel and Metabolic Flexibility

Nov 12, 2025

“In a 12-week randomized crossover trial, a modified ketogenic diet produced sustained physiological ketosis and improved daily function and quality of life compared with a usual diet supplemented with low-fat healthy-eating guidance.”

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How Meditation Connects With Immune and Gut Health

Aug 26, 2026

“In an early randomized workplace study, healthy employees who completed an eight-week mindfulness program showed a greater rise in antibodies after influenza vaccination than a waitlist group.”

gut microbiome inflammation immune system
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How Oat Beta-Glucan Lowers LDL and May Affect PFAS Levels

Aug 4, 2026

“Randomized trials and a meta-analysis show that at least three grams of oat beta-glucan per day can lower LDL by about five to seven percent, with high-molecular-weight products producing the most consistent effects.”

PFAS beta-glucan gut cholesterol
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How Omega-3 Status Relates to Inflammation, Muscle, and Longevity

Nov 27, 2023

“The excerpt also reviews controlled muscle studies: omega-3 attenuated loss during immobilization and increased the amino-acid-stimulated muscle-protein-synthesis response under tested conditions. These findings do not generalize to every dose or population.”

aging omega-3 inflammation pregnancy
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