Search results for genetics

“Genetically low plasma vitamin D levels are associated with higher mortality from respiratory infections, and SNPs in the vitamin D receptor that are associated with a higher risk of respiratory tract infections might play a role. In this clip, Dr. Rhonda Patrick discusses the role that genetics plays in the immune system.”

“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”

“A few examples of genes with common polymorphism discussed are MTHFR and folate, NBPF3 and vitamin B6, FUT2 and vitamin B12, BCMO1 and beta-carotene, FADS2 and omega-3 fatty acids, CYP2R1 and vitamin D, PEMT and choline as well as APOE4 and FOXO3.”

“While some forms of Parkinson's disease are genetic, most cases involve a complex interaction between genetic and environmental risk factors. In the early 1980s, intravenous drug users inadvertently injected a contaminated drug and developed parkinsonian symptoms overnight.”

“Genetic factors can impact plasma lipoprotein levels and the risk of coronary artery disease. Genes associated with elevated low-density lipoprotein (LDL) cholesterol levels have also been associated with increased heart disease risk, suggesting a causal relationship.”

“Recent discoveries in the field of aging research may have identified the signal that can manipulate the epigenome to restore proteins – including sirtuins – to their earlier, younger functional capacity.”

“What might be a surprise is that the body's response to carbohydrate and other components of the diet is highly personal – influenced by not only a person's metabolic profile, but also their gut microbiome.”

“A growing body of scientific evidence suggests that there is a correlation between decreased activation of the IGF-1 pathway and increased lifespan. Studies in worms and mice indicate that when the IGF-1 receptor is knocked out, the organisms remain disease-free and live longer.”