Link between sirtuin pathway and the Horvath Clock | David Sinclair

Parent Episode: Dr. David Sinclair on Informational Theory of Aging, Nicotinamide Mononucleotide, Resveratrol & More

The Horvath clock, a means of assessing a person's “epigenetic age," measures DNA methylation levels, which increase as a person ages, and can even predict how long a person will live. Recent discoveries in the field of aging research may have identified the signal that can manipulate the epigenome to restore proteins – including sirtuins – to their earlier, younger functional capacity. In this clip, Dr. David Sinclair describes how epigenomic modifications can influence how an organism ages, potentially reversing years of age-related damage.

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