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Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick discusses her supplement stack, avoiding microplastics, creatine for brain health, and mRNA vaccine autoimmunity risks.

“Even though the primary endpoints failed (NR did not improve insulin sensitivity or weight loss), he notes a meaningful signal in reduced liver fat—a 2% decrease in the NR group compared to a 0.2% reduction in the placebo group, a difference that didn't reach statistical significance, likely because subjects weren't randomized by liver fat and variability was high.”

“Since a driving force in the development of insomnia is change, especially change that affects relationships, employment, or family dynamics, Dr. Mason employs cognitive behavior techniques that help her patients identify what those changes are and develop strategies that promote, rather than hinder, sleep.”

“Supplementing with oral DHEA (usually 25–50 mg per day) can meaningfully boost testosterone levels, potentially improving symptoms like low energy, quality of life, and libido; however, limited evidence exists for improvements in menopausal symptoms, sexual function, cognition, or overall well being in normal women without adrenal insufficiency.”

“According to the latest research on fed vs. fasted exercise: If your workout lasts longer than 60 minutes, especially aerobic (endurance-based) sessions, eating beforehand tends to improve performance Your body has quick access to glucose, which helps you go longer and harder.”

“01:36:35 - How increased muscle mass helps achieve lower blood sugar levels – reducing overall mortality – and the potential for suboptimal glycemic control long before doctors identify it. 01:52:28 - Peter's 80% zone 2 / 20% VO2 max training protocol.”