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“Multiple age-related inputs can keep innate immune pathways active, including the senescence-associated secretory phenotype, mitochondrial damage and oxidative stress, debris released by injured cells, visceral adipose tissue inflammation, chronic infections, increased intestinal permeability, and dysbiosis.”

“Brighter days can support cognition and function in older adults Whole-day lighting of approximately 1,000 lux produced model-based relative reductions of 5% in cognitive decline, 19% in depressive symptoms, and 53% in the increase in functional limitations, compared with customary lighting near 300 lux, in a cluster-randomized trial across 12 elder-care facilities.”

“Practical ways to use short bouts Choose the version that matches the goal rather than forcing every short activity into one label: For a vigorous fitness stimulus Select a familiar movement such as stairs, a stationary bike, uphill walking, or a bodyweight circuit.”

Liquid biopsies, a non-invasive cancer screening technology that includes GRAIL's Galleri test, could transform early detection and treatment by analyzing tumor-derived cells and components.

“Hair follicles, however, have potent circadian-regulated repair mechanisms that correct and repair damaged DNA, allowing an irradiated hair cell to regenerate, unharmed. Experiments in mice have shown that these mechanisms are particularly effective after fasting.”

Dr. Rhonda Patrick explores blood tests to track health, statin alternatives, mitochondrial supplements, and vitamin B12 and autism risk in her latest Q&A.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Bruce explains that this may still leave people insufficient for long-term diseases. In light of his triage theory, this means a poor diet may have enough nutrition to prevent serious acute diseases but still lead to accelerated aging and long-term diseases.”

“This may be particularly important in the acute care setting where time is of the essence. In this clip, Dr. Roger Seheult describes how calcifediol may be used in an acute care setting to ameliorate low vitamin D status.”