Search results for insulin

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

“A network meta-analysis of 84 randomized trials found that aerobic exercise, HIIT, combined training, and resistance training alone all reduced visceral fat, while a separate meta-analysis found a modest reduction from resistance training across 34 studies.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“In this member Q&A clip, Dr. Rhonda Patrick explains the incretin hormones GIP and GLP-1. GLP-1 receptor agonists such as semaglutide increase glucose-dependent insulin signaling, reduce glucagon, slow gastric emptying, and act on appetite pathways in the brain.”

“A person's chronotype, whether they are an early riser or a night owl, may affect optimal exercise timing. Thus, some self-experimentation may help athletes, both elite and recreational, find their ideal training period for peak performance.”

“A proponent of the preventative health value of aggressively collecting data, Dr. Snyder's story is illustrative because, without his tracking of glucose, he may not have realized when the point at which his personal glucose management warranted seeking medical attention, potentially putting him at risk of more long-term deleterious effects.”

“Other research indicates that metformin inhibits the exercise-induced improvements in mitochondrial respiration and limits gains in lean body mass. In this clip, Dr. Rhonda Patrick describes the many open questions that remain regarding the interaction between metformin and exercise at the molecular level.”

“Diet plays a key role in the prevention of Alzheimer's disease. The Ketoflex 12/3 diet, a form of time-restrictive eating that limits the period during which a person eats to a 12-hour window at least three hours before bedtime, promotes the production of ketones.”

“Longitudinal studies showed that people with type 2 diabetes taking metformin lived 15 percent longer than healthy controls not taking the drug. This raises the question as to whether the longevity benefits of metformin may extend to healthy people.”

“But implementing a ketogenic diet is challenging. In this Aliquot, Dr. Dominic D'Agostino explains how to avoid side effects on a ketogenic diet, provides valuable pointers for success, and explains how the diet might help preserve muscle mass.”