Related Episodes for Small vessel disease

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Whereas its link to diabetes is well known, what is likely underappreciated is that refined sugar may be linked to as many as 200,000 deaths worldwide each year from diabetes, cardiovascular disease, and cancer combined. Refined sugar also affects the brain.”

“One hypothesis is that DNA repair enzymes, known as PARP (poly ADP-ribose polymerase), might be using up more NAD+ to fix the accumulated DNA damage that occurs with age. Alternately, the cellular pathway that recycles NAD+ may decline in performance with age.”

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“In the past, humans' primary exposure to blue light was from the sun, but in modern times, electronic devices – TVs, computer screens, and cell phones – expose us to increasing amounts of blue light, often during times of the day or night that are out of sync with our bodies' natural rhythms.”

“Although the findings of a large meta-analysis published in the journal Annals of Internal Medicine indicated that there was no evidence to support the notion that consumption of saturated fat increased the risk of heart disease, the studies on which their conclusions were based were primarily observational.”

“People that used the sauna 2-3 times per week had a 20% lower risk of Alzheimer’s disease, and those that used the sauna 4-7 times per week had a 60% lower risk of Alzheimer's disease, compared to men that used the sauna 1 time per week.”

“Ultimately, we all have to weigh the merits and the trade-offs of portable devices for ourselves and our children individually, but it might mean holding out on the tablet until they're a little older, setting rules around it, and certainly demonstrating our own self-discipline in their use.”

“The comparison depends on what a dietary fat replaces. Randomized trials show that replacing palmitic acid, a common saturated fat, with unsaturated fats lowers LDL cholesterol and apolipoprotein B without a consistent effect on glucose, insulin, or C-reactive protein.”