“Diet stands out as low-hanging fruit for influencing our lifespan. Optimizing macronutrient intake, practicing time-restricted eating, and consuming healthful bioactive compounds are critical aspects of a healthy diet. In part II of this two-part Aliquot, Drs.”
“In this Aliquot, we share a variety of segments from different interviews covering some of the unconventional effects of omega-3 fatty acids and how to overcome some of the roadblocks to obtaining these effects.”
“A healthy intestinal barrier limits the transport of pathogens and endotoxins from the gut to the bloodstream; however, increased gut permeability (known as "leaky gut") raises endotoxin levels, leading to metabolic endotoxemia.”
“The immune system has strategies for filtering these autoimmune cells out of circulation; however, this filter can malfunction due to age, genetic predisposition, disruption of the gut barrier and gut microbiota, or other environmental exposures.”
“Exercise is a huge driver of how well we age because it induces profound molecular shifts that support immune health and might even protect our telomeres – indicators of aging. Exercise might help forestall certain age-related diseases, such as Parkinson's disease, too.”
“But could aging become reversible in the future? Technologies like interrupted cellular reprogramming, in combination with future advances in the field of epigenetics, offer the promise that scientists may eventually be able to develop the means to reverse aging.”
“Dietary fiber is a broad term that refers to the non-digestible components of fruits and vegetables. Gut microbes break down certain types of fiber, releasing micronutrients trapped in the fiber matrix and producing beneficial metabolic byproducts, such as short-chain fatty acids.”
“Sugar substitutes are food products or additives that provide the sweet taste of sugar, without the calories. Evidence suggests that sugar substitutes have surprising effects on human metabolism and these effects vary person-to-person, based on the overall makeup of an individual's gut microbiome.”
“Building muscle mass in one's early years is essential for staving off the age-related loss of muscle mass and may promote longevity. In this Aliquot, Dr. Stuart Phillips discusses the importance of building muscle through resistance training and why starting early is important.”
“Having sufficient muscle mass markedly reduces a person's risk of dying prematurely. Although some studies suggest that eating less protein promotes longevity, those studies might not take into account the periods of disuse and disability that often occur in real life.”