Related Episodes for How stressed plants communicate to our genes (to our benefit) | David Sinclair

“An enriched marine-oil study produced time- and dose-dependent increases in specialized pro-resolving mediators and altered blood-cell responses over 24 hours; it tested biomarkers, not disease prevention. Exercise, sauna, and cruciferous vegetables act through different pathways.”

“- Practical details like temperature and duration of sauna use, the difference between a dry, wet and infrared sauna, sauna timing, as well as other forms of heat stress such as steam showers, hot baths, and hot yoga.”

“For people concerned about LDL cholesterol, paper-filtered or instant coffee offers a practical way to retain many coffee polyphenols while reducing diterpene exposure. The machine and container also matter.”

“In this clip from Dr. Rhonda Patrick's appearance on The Dan Bongino Show, she explains that the amount of EPA and DHA needed to change the Omega-3 Index varies with baseline status, body size, formulation, diet, and adherence.”

“Brady Holmer turns the protocol into a weekly framework: one interval session, one longer easy session, additional base-pace activity, active recovery, and at least two resistance sessions. Dr. Patrick emphasizes the progressive build.”

“Even though the primary endpoints failed (NR did not improve insulin sensitivity or weight loss), he notes a meaningful signal in reduced liver fat—a 2% decrease in the NR group compared to a 0.2% reduction in the placebo group, a difference that didn't reach statistical significance, likely because subjects weren't randomized by liver fat and variability was high.”

“The oversimplified view that high-density lipoprotein (HDL) cholesterol is good, and low-density lipoprotein (LDL) cholesterol is bad has led to misunderstandings of the relationship between cholesterol and cardiovascular disease risk.”

“Preliminary findings from a study analyzing UK Biobank data with over 25,000 participants suggest that even 3-4 minutes of VILPA daily could reduce all-cause mortality risk by 25-30%.”

“However, the term "fasting" can comprise a variety of subtypes. Intermittent fasting, a term lacking specificity, usually refers to interventions such as alternate-day fasting, fasting one day per week, or a five:two eating pattern (fasting for two days per week).”

“The most compelling human signal appears when the brain is under acute strain. In a randomized crossover study, a single dose of 0.35 grams per kilogram during 21 hours of sleep deprivation changed cerebral energy metabolites and preserved selected measures of cognitive performance.”