Related Episodes for Can limiting protein intake (or other selective nutrient depletion) induce autophagy?

“Diet plays a key role in the prevention of Alzheimer's disease. The Ketoflex 12/3 diet, a form of time-restrictive eating that limits the period during which a person eats to a 12-hour window at least three hours before bedtime, promotes the production of ketones.”

“Time-restricted eating can help some people reduce eating opportunities, but controlled trials have not found a consistent visceral-fat advantage over matched dietary counseling or calorie restriction.”

“Time-restricted eating – a term coined by Dr. Panda and his colleagues – has been adopted by the popular press as a form of intermittent fasting. It does not explicitly involve reducing calories but rather is an eating pattern wherein a person confines the time of day that they eat to a limited window and fasts for the remainder of the day.”

“Time-restricted eating, in particular, has the potential to realign the body's circadian rhythms. In this clip, Dr. Rhonda Patrick describes some of the different types of fasting and identifies the advantages associated with each.”

“In a four-month randomized trial of 88 overweight, untrained middle-aged adults, daily doses of 500 or 1,000 milligrams improved some muscle and mitochondrial measures, while the primary outcome of peak power did not significantly improve.”

“Dr. Brooks's exact practice of waking 96 minutes before dawn comes from the Vedic concept of Brahma Muhurta rather than a tested clinical protocol. Creatine may provide modest cognitive benefits in some settings, although results in healthy adults are mixed.”

“Dr. Schoenfeld says the situation is likely more complex and nuanced. For example, a marathon runner will have difficulty with hypertrophy, probably due to overtraining rather than intracellular signaling negatively affecting muscle development.”

“Young people usually bounce back from muscle loss quite quickly, but for older adults, the stakes are higher, as repeated inactivity can lead to irreversible muscle loss and diminished strength, critically impacting their daily activities.”

“Whereas fasting turns off multiple pathways associated with aging, such as mTOR, IGF-1, growth hormone, and others, eating for optimal fitness activates these important processes. This Aliquot features Drs. Guido Kroemer, Dominic D'Agostino, Valter Longo, Peter Attia, and Rhonda Patrick.”

“Having sufficient muscle mass markedly reduces a person's risk of dying prematurely. Although some studies suggest that eating less protein promotes longevity, those studies might not take into account the periods of disuse and disability that often occur in real life.”