Related Episodes for Dominic D'Agostino, Ph.D. on Modified Atkins Diet, Ketosis, Supplemental Ketones and More

“A small randomized trial in trained athletes found that 20 milligrams per day for two weeks increased total antioxidant capacity and glutathione peroxidase and reduced post-training DNA damage versus placebo; it did not test performance or long-term adaptation.”

“Whereas fasting turns off multiple pathways associated with aging, such as mTOR and IGF-1, eating for optimal fitness activates these important processes. The IGF-1 pathway, in particular, plays key roles in growth and is strongly associated with cancer.”

“In a small trial of 30 people with stable heart failure, 1,000 milligrams twice daily approximately doubled whole-blood NAD and appeared tolerable while supporting further study rather than proving treatment benefit.”

“In a randomized crossover trial, a standardized ashwagandha extract produced a modest testosterone increase in overweight men with mild fatigue, while a meta-analysis of five tongkat ali trials found a positive pooled effect with substantial variation across studies.”

“Randomized trials and a meta-analysis show that at least three grams of oat beta-glucan per day can lower LDL by about five to seven percent, with high-molecular-weight products producing the most consistent effects.”

“In the prospective Framingham Offspring Study, people in the highest red-blood-cell DHA group had approximately 49 percent lower risk of developing Alzheimer's disease than those in the lowest group.”

“Melatonin appears in the comparison as a personal, goal-specific choice rather than a universal nightly supplement. Dr. Patrick also discusses glycine, collagen, myo-inositol, and other non-overlapping items with different levels of evidence.”

“In a 12-week randomized trial of 291 adults living in a region of China with substantial air pollution, a broccoli-sprout beverage increased urinary excretion of a benzene metabolite by 61 percent and an acrolein metabolite by 23 percent.”

“In a randomized trial of 57 children with autism spectrum disorder, a caregiver-rated secondary behavior scale improved and biomarker changes involved glutathione, mitochondrial, inflammatory, and heat-shock pathways, while the primary clinical outcome was similar between groups.”

“In this Institute for Functional Medicine excerpt, Dr. Rhonda Patrick frames omega-3 intake as beneficial and argues that low contaminant exposure should be weighed against the nutritional value of EPA and DHA. Her benefit-risk view does not mean omega-3 negates mercury or PCB toxicity.”