Related Episodes for Supplementing with exogenous ketone esters vs. eating a ketogenic diet | Eric Verdin

“In this FoundMyFitness interview clip with Dr. Rhonda Patrick, Dr. Layne Norton places creatine monohydrate in his highest evidence tier because it supports repeated high-intensity performance, strength, and gains in lean mass.”

“However, she considers the amounts in its proprietary superfood, extract, and probiotic blends too small to justify expecting the broader benefits implied by those categories. She presents this as her assessment of the product label.”

“In a separate analysis of seven intervention trials involving people with type 2 diabetes, HbA1c fell by about 0.71 percentage points, total cholesterol by 23 mg/dL, and LDL cholesterol by 22 mg/dL.”

“In a six-month trial of adults with peripheral artery disease, a flavanol-rich cocoa beverage improved six-minute walking distance measured 2.5 hours after dosing. In older adults with mild cognitive impairment, higher-flavanol cocoa improved selected verbal-fluency and executive-function tests over eight weeks.”

“Dr. Patrick explains that she uses zinc lozenges only during exposure or the earliest signs of illness, often totaling roughly 80 to 100 milligrams per day for a short period. Small randomized zinc-acetate lozenge trials have produced mixed results, with one reporting a shorter cold and another finding no faster recovery with more adverse effects.”

“However, exercising while taking a non-steroidal anti-inflammatory agent (NSAID) may blunt the initial rush of acute inflammation and negate some of the long term health effects of exercise.”

“A large meta-analysis found that protein supplementation improved resistance-training gains in muscle size and strength, with little additional lean-mass benefit above an estimated total intake of about 1.6 grams per kilogram per day for most participants.”

“A meta-analysis of 19 randomized trials involving 1,683 participants found modest average improvements, including about seven minutes less time to fall asleep and eight minutes more total sleep. Product quality can make dose selection difficult.”

“In a randomized crossover trial, a standardized ashwagandha extract produced a modest testosterone increase in overweight men with mild fatigue, while a meta-analysis of five tongkat ali trials found a positive pooled effect with substantial variation across studies.”

“Randomized trials and a meta-analysis show that at least three grams of oat beta-glucan per day can lower LDL by about five to seven percent, with high-molecular-weight products producing the most consistent effects.”