Related Episodes for Eating to extend healthspan: overnutrition vs undernutrition | Ray Cronise

“Premenopausal females have much lower rates of cardiovascular disease than similarly aged males because of the protective effects of estrogen, but after menopause, there's not much of a difference, and cardiometabolic risk factors actually worsen in females during the menopause transition, indicating this may be a crucial time for exercise intervention to protect the cardiovascular system.”

“An enriched marine-oil study produced time- and dose-dependent increases in specialized pro-resolving mediators and altered blood-cell responses over 24 hours; it tested biomarkers, not disease prevention. Exercise, sauna, and cruciferous vegetables act through different pathways.”

“Unique qualities of the marine omega-3 fatty acids EPA and DHA There are several omega-3 fatty acids, but the ones that have the greatest relevance for human health are the two identified in the Inuit's blood – EPA and DHA – as well as alpha-linolenic acid (ALA), which is found in a wide variety of seeds, nuts, and their oils.”

“- Practical details like temperature and duration of sauna use, the difference between a dry, wet and infrared sauna, sauna timing, as well as other forms of heat stress such as steam showers, hot baths, and hot yoga.”

“I am simply choosing not to blend them into my blueberry smoothie when the goal is to maximize polyphenol exposure.".(https://www.foundmyfitness.com/episodes/blueberries)'] A 2023 banana-smoothie study caught Rhonda's attention because the effect was unusually large and the mechanism made biological sense.”

“When humans ingest these compounds, our cells "read" their chemical signals and switch on cellular mechanisms that protect us not only from the plant compound but also the environmental stressors to which we are exposed on a daily basis, such as air pollution or overexposure to UV radiation.”

“In this clip from Dr. Rhonda Patrick's appearance on The Dan Bongino Show, she explains that the amount of EPA and DHA needed to change the Omega-3 Index varies with baseline status, body size, formulation, diet, and adherence.”

“Brady Holmer turns the protocol into a weekly framework: one interval session, one longer easy session, additional base-pace activity, active recovery, and at least two resistance sessions. Dr. Patrick emphasizes the progressive build.”

“Even though the primary endpoints failed (NR did not improve insulin sensitivity or weight loss), he notes a meaningful signal in reduced liver fat—a 2% decrease in the NR group compared to a 0.2% reduction in the placebo group, a difference that didn't reach statistical significance, likely because subjects weren't randomized by liver fat and variability was high.”

“Preliminary findings from a study analyzing UK Biobank data with over 25,000 participants suggest that even 3-4 minutes of VILPA daily could reduce all-cause mortality risk by 25-30%.”