Related Episodes for How the gut microbiome regulates immune cell types

“Scientists are investigating the effects that Wim Hof's breathing methods have on the immune system. Study results showed that individuals trained in his breathing practices produced adrenaline when injected with a bacterial endotoxin, potentially affecting the immune response.”

“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”

“Dr. Huberman’s practical range is deliberately cautious: not drinking avoids the exposure, and lower weekly intake creates less burden than a drink every night or heavier episodes.”

“For example, sulforaphane promotes the urinary excretion of benzene and acrolein, toxic compounds present in air pollution. But sulforaphane also demonstrates remarkable antibacterial activity: It reduces populations of Helicobacter pylori, or H.”

“These changes increase infection risk, weaken vaccine responses, and reduce early cancer surveillance. Yet immune aging is not fixed. Movement, sleep, stress regulation, temperature exposure, and nutrition shape immune cell balance and inflammatory activity over time.”

“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”

“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”

“As for this last point in particular, but also all conversations surrounding severe life-altering diagnosis like cancer, these clips are not meant to serve as a substitute for medical advice.”

“Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu.”

“Having a healthy, robust immune system is crucial for our survival. Critical players in the body's antiviral immune response are interferons. Certain lifestyle behaviors can boost interferon production and immune function, including sleep, vitamin D, and hot hydrotherapy.”