Related Episodes for Growth hormone defect protects against cancer, diabetes, and cognitive decline | Valter Longo

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”

“Recent studies have identified a connection between an impaired interferon response and severe COVID-19 disease. Strategies that increase the body's core temperature – analogous to having a fever – may be beneficial early in COVID-19 illness.”

“In this excerpt from Dr. Rhonda Patrick's A4M LongevityFest 2023 keynote, she argues that vigorous exercise is one of the most powerful tools for healthy aging because it can raise cardiorespiratory fitness.”

“In 27 men with metabolic syndrome, four four-minute intervals near 90 percent of peak heart rate improved VO2 max more than work-matched moderate exercise. A two-year randomized trial used a broader progressive program in healthy, sedentary adults around age 53.”

“Controlled human studies support acute brain-related responses to high-intensity exercise. Six short all-out cycling intervals improved selected learning and executive measures while increasing circulating BDNF, IGF-1, and VEGF; lactate tracked several of these changes.”

“Dr. Patrick recommends vigorous intervals when moderate training does not improve an individual’s VO2 max and presents repeated one-minute efforts and the Norwegian 4-by-4 as practical options.”

“A large meta-analysis found that protein supplementation improved resistance-training gains in muscle size and strength, with little additional lean-mass benefit above an estimated total intake of about 1.6 grams per kilogram per day for most participants.”

“People with Parkinson's disease can benefit from engaging in an intense exercise program that incorporates both a skilled and an aerobic component. Activities that involve gait and balance training are particularly useful.”

“How too much iron can lead to protein aggregation and how vitamin D can prevent it. A program, directed by Gordon, called the Caenorhabditis Intervention Testing Program which tests potential longevity compounds that may extend the lifespan of several different species of worms.”

“Dr. Rhonda Patrick talks at SF Nerd Nite about transgenerational effects of caloric restriction on longevity, B-vitamins silencing bad genes, cognitive stimulation reversing neurodegenerative disease, exercise increases neurogenesis, and ways in which vitamin D might influence aging.”