Related Episodes for The Underlying Mechanisms of Depression

“Dr. Patrick recommends transferring food to glass or ceramic before heating and treating BPA-free labels cautiously because replacement chemicals can have their own biological activity.”

“Whereas its link to diabetes is well known, what is likely underappreciated is that refined sugar may be linked to as many as 200,000 deaths worldwide each year from diabetes, cardiovascular disease, and cancer combined. Refined sugar also affects the brain.”

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“Most common graying is strongly related to age and genetics, but selected observations suggest that stress, nutrient status, and cellular energy metabolism can influence pigment in some circumstances.”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“Although the findings of a large meta-analysis published in the journal Annals of Internal Medicine indicated that there was no evidence to support the notion that consumption of saturated fat increased the risk of heart disease, the studies on which their conclusions were based were primarily observational.”

“Compared with one sauna session per week, four to seven weekly sessions were associated with 66% lower dementia hazard and 65% lower Alzheimer's disease hazard, showing a strong dose-related pattern in this population. A second Finnish cohort followed 13,994 men and women.”

“A staggering 60% of all calories Americans consume come from ultra-processed foods that fail to induce proper satiety, remain cheaper than whole foods, and hijack our dopamine reward pathways, pushing us to overeat, incentivizing unhealthy food choices, and reinforcing addictive eating behaviors.”

“This is a video on how to plausibly increase the sulforaphane created from the glucoraphanin in your broccoli sprouts by up to 3.5-fold, based on the results of a 2004 Phytochemistry paper entitled "Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli."”

“A separate small randomized trial in healthy adults found that 200 milligrams per day for four weeks improved selected self-reported stress and sleep measures, but larger confirmatory trials and direct testing of the complete stack are still needed.”