Related Episodes for How gut microbiome is affected by circadian rhythm and sleep deprivation | Matthew Walker

“Researchers treated patients with major depressive disorder with heat so that their core body temperature reached temperatures equivalent to those experienced with sauna use. Following just one treatment session, subjects experienced elevations in mood that lasted for several weeks.”

“Time-restricted eating, which involves taking in food within a specific period of the day and fasting for the remainder, can improve certain biomarkers of health - even without weight loss. One theory is that this eating pattern coordinates food intake with the body's peak metabolism period.”

“In a short controlled protocol in healthy young men, five nights of restricted sleep impaired glucose tolerance and muscle mitochondrial function, while participants who added high-intensity interval exercise did not show the same changes.”

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”

“In this Institute for Functional Medicine excerpt, Dr. Rhonda Patrick describes her personal 10–15-minute routine, usually five days per week: Tabata-style all-out efforts alternating with Zone 3 and sometimes Zone 2 recovery, plus resistance training.”

“Dr. Brooks's exact practice of waking 96 minutes before dawn comes from the Vedic concept of Brahma Muhurta rather than a tested clinical protocol. Creatine may provide modest cognitive benefits in some settings, although results in healthy adults are mixed.”

“In this Aliquot, Drs. Satchin Panda, Andrew Huberman, Layne Norton, Brad Schoenfeld, Martin Gibala, and I examine how circadian biology, training intensity, and life schedule shape exercise timing. We also explore what that means for deciding when to train.”

“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”

“Time-restricted eating, which involves taking in food within a small window of time during the day and fasting for the remainder, can improve certain biomarkers of health – even without weight loss – to improve overall health. In Part I of this two-part segment, Drs.”

“Coordination of meal timing with the circadian rhythm can reduce markers of inflammation and affect aspects of metabolic health, including glucose regulation and insulin sensitivity. Animal studies suggest that overnight fasting induces autophagy.”