Related Episodes for Psychedelic drugs, psilocybin, and transcendent experiences as antidepressants | Charles Raison

Dr. Rhonda Patrick discusses nicotinamide riboside, biomarkers, belly fat loss, sex-specific health, curcumin & ashwagandha safety.

“One hypothesis is that DNA repair enzymes, known as PARP (poly ADP-ribose polymerase), might be using up more NAD+ to fix the accumulated DNA damage that occurs with age. Alternately, the cellular pathway that recycles NAD+ may decline in performance with age.”

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“Although the findings of a large meta-analysis published in the journal Annals of Internal Medicine indicated that there was no evidence to support the notion that consumption of saturated fat increased the risk of heart disease, the studies on which their conclusions were based were primarily observational.”

“Compared with one sauna session per week, four to seven weekly sessions were associated with 66% lower dementia hazard and 65% lower Alzheimer's disease hazard, showing a strong dose-related pattern in this population. A second Finnish cohort followed 13,994 men and women.”

“A systematic review and meta-analysis of 44 randomized trials found that berberine improved several surrogate measures, including inflammatory biomarkers, stroke-related neurological deficit scores, and carotid intima-media thickness.”

“In this video, Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles.”

“Dr. Panda discusses the effects of time-restricted feeding on systemic inflammation; time-restricted eating as an opportunity for night-time repair that may prevent intestinal hyperpermeability (i.e., leaky gut), a primary source of systemic inflammation; and how the timing of macronutrients may differentially affect gut permeability.”

“The trial found selected changes in antioxidant capacity, immune-cell apoptosis, and inflammatory gene expression, while several main circulating oxidative-stress measures did not differ from plain water. Clinical findings remain modest and depend on the population and outcome.”

“Pooled intervention data suggest that about 1.5 to 2 grams of combined EPA and DHA per day can raise the Omega-3 Index in many adults over several months, although individual responses vary.”