Related Episodes for How Sauna Use May Protect the Aging Brain

Dr. Rhonda Patrick discusses nicotinamide riboside, biomarkers, belly fat loss, sex-specific health, curcumin & ashwagandha safety.

Dr. Rhonda Patrick reviews the evidence for nattokinase, how oat beta-glucans may aid with PFAS excretion, and HRT for APOE4 carriers.

Dr. Rhonda Patrick discusses sunscreen safety, HIIT & brain health, diet, omega-3s, urolithin A, sulforaphane, homocysteine, peptides, and CoQ10.

“One hypothesis is that DNA repair enzymes, known as PARP (poly ADP-ribose polymerase), might be using up more NAD+ to fix the accumulated DNA damage that occurs with age. Alternately, the cellular pathway that recycles NAD+ may decline in performance with age.”

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“Although the findings of a large meta-analysis published in the journal Annals of Internal Medicine indicated that there was no evidence to support the notion that consumption of saturated fat increased the risk of heart disease, the studies on which their conclusions were based were primarily observational.”

“The comparison depends on what a dietary fat replaces. Randomized trials show that replacing palmitic acid, a common saturated fat, with unsaturated fats lowers LDL cholesterol and apolipoprotein B without a consistent effect on glucose, insulin, or C-reactive protein.”

“Although scientists have identified other lifestyle behaviors that can help prevent the build-up of amyloid plaques by boosting the capacity for glymphatic clearance – such as exercise and adequate intake of omega-3 – the most important factor by far is a good night's sleep, especially deep sleep.”

“There is so much to say when we talk about the NRF2 pathway and isothiocyanates like sulforaphane that we had to pack it into 47 minutes and break it into a few key sections. Key sections: For a more in-depth breakdown click the timeline link at the top of this page!”