How time-restricted eating affects leaky gut and systemic inflammation | Satchin Panda

Parent Episode: Dr. Satchin Panda on Practical Implementation of Time-Restricted Eating & Shift Work Strategies

A leaky gut, otherwise known as intestinal permeability, is a condition in which gaps form between the tight junctions of the endothelial cells that line the gut. These gaps allow pathogens like bacteria or endotoxins – toxins that are released when bacteria die – to leak through the intestinal wall and pass directly into the bloodstream, potentially triggering an acute inflammatory reaction. Leaky gut has been linked with a number of chronic diseases, including Alzheimer’s disease and cardiovascular disease. But overnight fasting during time-restricted eating provides the gut time to heal, preventing leaky gut. In this clip, Dr. Satchin Panda describes the role fasting plays in maintaining a healthy gut and reducing systemic inflammation.

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