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“In fact, methylation and demethylation are critical processes in development. Interfering with the enzymes that carry out these two opposing processes can play critical roles in epigenetic age, ultimately affecting aging, disease, and death.”

“However, critical metabolic differences between mice and humans make it difficult to extrapolate these findings to humans. In this clip, Dr. Guido Kroemer describes the current state of knowledge about the minimum amount of time required for fasting-induced autophagy in humans.”

“As we age, our hair changes: It often turns gray and becomes finer, and it might even fall out—permanently. There are seemingly millions of hair care products available, and many of them contain chemicals that may harm our hair or, even worse, harm our health. In this Aliquot, I explore the various ways to prevent hair loss and promote healthy hair.”

“Dr. Rhonda Patrick talks at SF Nerd Nite about transgenerational effects of caloric restriction on longevity, B-vitamins silencing bad genes, cognitive stimulation reversing neurodegenerative disease, exercise increases neurogenesis, and ways in which vitamin D might influence aging.”

“In REDUCE-IT, prescription icosapent ethyl lowered major ischemic events among statin-treated adults with elevated triglycerides, while atrial fibrillation or flutter requiring hospitalization occurred more often in the treatment group.”

“Protein is essential for building and maintaining muscles. Aiming for about 1.2 to 1.6 grams of protein per kilogram of body weight (about 0.5 to 0.7 grams per pound) is optimal for maintenance on the lower end and building muscle on the higher end.”

“In this Aliquot, I'll explore how to recognize and address iron deficiency, the unique challenges of iron overload in aging, the ways alcohol may influence brain iron, and how infants tightly regulate iron as a built-in defense against infection.”

“Dr. Huberman therefore uses a subjective ‘wall’ model rather than a rigid prescription: enter safely, notice the first strong urge to leave, and practice staying calm long enough to complete the planned exposure.”

“In a controlled crossover study of eight healthy men, a high-PPO banana smoothie produced an 84% lower peak concentration of circulating flavan-3-ol metabolites than a flavan-3-ol capsule.”

“A later Framingham analysis followed 2,240 adults for 11 years and found that a red-cell fatty acid model including the Omega-3 Index predicted all-cause mortality about as well as a model using several standard cardiovascular risk factors.”