Ranked by shared topics, with one result from each original episode.
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“In a small trial involving adults with obesity, a ketone monoester improved one processing-speed task and selected brain blood-flow measures, providing an early signal for further research. Temperature can also shape alertness and sleep preparation.”
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“Dr. Patrick starts with the Finnish observational evidence: frequent sauna use and sessions longer than 19 minutes were associated with lower cardiovascular mortality in middle-aged men. That evidence informs her routine, but it does not make her temperature, duration, or frequency a universal prescription.”
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“Manipulating the core body temperature through hot baths, showers, or saunas – which can have a paradoxical effect on reducing core body temperature – can have dramatic effects on our ability to fall asleep.”
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“In this clip, Dr. Michael Snyder discusses how people age in distinct ways and at varying rates and how knowing our "ageotype" might offer targets for preventing age-related diseases.”
“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”
“As for this last point in particular, but also all conversations surrounding severe life-altering diagnosis like cancer, these clips are not meant to serve as a substitute for medical advice.”
“Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu.”
“In the setting of COVID-19, vitamin D deficiency drives poor outcomes. Treating patients with calcifediol, a prescription vitamin D analog, might be more effective at increasing vitamin D to therapeutic levels.”
“Having a healthy, robust immune system is crucial for our survival. Critical players in the body's antiviral immune response are interferons. Certain lifestyle behaviors can boost interferon production and immune function, including sleep, vitamin D, and hot hydrotherapy.”
“A growing body of evidence indicates that the fasting-mimicking diet may be beneficial in treating autoimmune disorders. In these Aliquot segments, Dr. Rhonda Patrick and Dr. Valter Longo describe the roles that diet and fasting play in maintaining or restoring proper immune function.”