Related Episodes for What Cocoa Flavanols May Do for Circulation and Cognition

“The majority of glutamine administered orally is taken up by the liver and gut, with little ending up in the bloodstream. Dr. D'Agostino discourages supplementing with glutamine for patients with cancers of the gastrointestinal tract and even recommends they avoid high glutamine containing foods.”

“Although the vast majority of supplement manufacturers do not take steps to preserve the integrity of their products and some have made misleading claims about their products' efficacy, a few reputable manufacturers produce quality supplements that demonstrate beneficial effects against prostate cancer.”

“The most compelling human signal appears when the brain is under acute strain. In a randomized crossover study, a single dose of 0.35 grams per kilogram during 21 hours of sleep deprivation changed cerebral energy metabolites and preserved selected measures of cognitive performance.”

“A recent meta-analysis also found small benefits in selected cognitive domains, including memory and processing speed, with responses that may depend on age, diet, baseline stores, stress, dose, and the cognitive test used.”

“A separate six-week randomized study in 30 healthy young adults found that neither 10 nor 20 grams per day improved the tested cognitive outcomes compared with placebo. The result is an important counterweight to the acute sleep-deprivation experiment.”

“Healthy, well-nourished adults can usually synthesize enough, and athlete trials have not found consistent improvements in immune measures, aerobic performance, body composition, or intestinal permeability from routine supplementation.”

“Dr. David Sinclair takes roughly a gram of each every day with caffeinated coffee – a combo that he asserts gives him a lot of energy. In this clip, Dr. David Sinclair describes his personal resveratrol and nicotinamide mononucleotide supplementation habits.”

“Dr. Patrick explains that she uses zinc lozenges only during exposure or the earliest signs of illness, often totaling roughly 80 to 100 milligrams per day for a short period. Small randomized zinc-acetate lozenge trials have produced mixed results, with one reporting a shorter cold and another finding no faster recovery with more adverse effects.”

“Her practical message is to reduce the frequency and size of large glucose exposures. Foods with intact fiber, protein, and minimally processed carbohydrates digest more slowly than refined added sugar, while regular exercise gives skeletal muscle a large destination for circulating glucose.”

“In a two-year trial of 237 postmenopausal women, approximately 9 to 10 grams per day combined with resistance training and walking did not add a bone-density benefit, so its role is better framed around muscle and physical function.”