Related Episodes for How Creatine Dose Relates to Muscle and Brain Energy

“Dr. D'Agostino cautions against confusing a Westernized obesogenic high-fat diet with a ketogenic diet. In a well-designed preclinical study, researchers fed mice a cyclic ketogenic diet starting at midlife and observed improved healthspan, cognition, and brain function.”

“Dr. Patrick begins with a prospective Finnish cohort in which men reporting four to seven sauna sessions per week had lower dementia and Alzheimer's disease incidence than men reporting one session. The study is observational, male-only, and cannot prove that sauna caused the lower risk.”

“In this clip, Dr. Ruth Patterson discusses how healthful choices, such as even modest weight loss, can have beneficial effects that reduce the risk of breast cancer and a variety of other diseases.”

“Preliminary findings from a study analyzing UK Biobank data with over 25,000 participants suggest that even 3-4 minutes of VILPA daily could reduce all-cause mortality risk by 25-30%.”

“Longer-term nutrient status offers another perspective: in a randomized trial of adults with overweight or obesity, 15 grams of psyllium daily for three months did not significantly alter serum micronutrient concentrations relative to control.”

“In a six-month trial of adults with peripheral artery disease, a flavanol-rich cocoa beverage improved six-minute walking distance measured 2.5 hours after dosing. In older adults with mild cognitive impairment, higher-flavanol cocoa improved selected verbal-fluency and executive-function tests over eight weeks.”

“Drinking two to three cups per day is linked to roughly a 60% reduced risk of developing diabetes, a statistic that highlights coffee's robust metabolic benefits that arise from its ability to activate AMP-activated protein kinase (AMPK), a critical regulator of cellular energy metabolism.”

“Timing provides a practical compromise. Dr. van Loon favors protecting the first several hours after resistance or endurance training, then placing cold exposure later in the day or on a recovery day when muscle adaptation is the priority.”

“Other hormetic responses to cold exposure include increased production of PGC1-alpha, a protein that promotes mitochondrial biogenesis, the production of new, healthy mitochondria, and the activation of brown fat – a phenomenon once thought to occur only in newborns, but now known to occur in adults, especially after cold exposure.”

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”