Related Episodes for Tim Ferriss’ ketogenic diet hypothesis for Lyme disease

“Controlled studies have found higher overnight glucose after an identical dinner eaten at 10 PM instead of 6 PM and a larger glucose response when food intake occurs close to habitual bedtime during elevated endogenous melatonin.”

“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”

“Dr. Huberman’s practical range is deliberately cautious: not drinking avoids the exposure, and lower weekly intake creates less burden than a drink every night or heavier episodes.”

“Modulating autophagy – through fasting and exercise (which both increase acetyl CoA) or intake of nutrients like spermidine – represents a promising therapeutic approach for extending human lifespan and healthspan.”

“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”

“Time-restricted eating, which involves taking in food within a small window of time during the day and fasting for the remainder, can improve certain biomarkers of health – even without weight loss – to improve overall health. In Part I of this two-part segment, Drs.”

“Coordination of meal timing with the circadian rhythm can reduce markers of inflammation and affect aspects of metabolic health, including glucose regulation and insulin sensitivity. Animal studies suggest that overnight fasting induces autophagy.”

“Insulin-like growth factor-1, or IGF-1 for short, is a protein that plays critical roles in major growth pathways in the human body. It influences nearly every tissue in the body, especially developmental growth, skeletal muscle and neurons.”

“The timing of eating and exercise, especially in elite athletes, hasn't been studied and may, in fact, require self-experimentation by the athletes to identify the perfect interval of fasting to support their optimal performance.”

“Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu.”