Ranked by shared topics, with one result from each original episode.
Clip
“Normalizing the timing of food intake via time-restricted eating may help restore microbiome composition, potentially offsetting the increased disease risk. In this clip, Dr. Eran Elinav describes how the circadian rhythmicity of the microbiome is regulated and how this affects human health.”
Clip
“In conjunction with a restricted eating window, meal frequency can also play a role. Two meals a day may be optimal for individuals who are predisposed to gaining weight while people not prone to weight gain may prefer to eat three times a day.”
Clip
“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”
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“In a controlled five-week crossover trial involving men with prediabetes, an early six-hour eating window with dinner before 3 p.m. improved insulin sensitivity, pancreatic beta-cell responsiveness, blood pressure, oxidative stress, and appetite without causing weight loss.”
Episode
“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”
“In this Aliquot, cardiologist Ben Levine, nutritional scientist and champion powerlifter Layne Norton, and I discuss the importance of recovery, how best to approach it, and some surprising, often overlooked aspects of this important part of fitness.”
“From THC, CBD, alcohol, caffeine, and nicotine to melatonin, magnesium, glycine, and calming botanicals, these compounds can either support restorative sleep or subtly hijack it, changing REM, deep sleep, and circadian timing in ways we often do not feel until the next day.”
“In this Aliquot, sleep scientist Dr. Michael Grandner explains why sleep apnea is so often missed, how these nightly breathing disturbances affect the body, and which treatments can meaningfully improve sleep and long-term health.”
“The different stages of sleep provide crucial periods during which the body recalibrates to promote both mental and physical well-being. In this clip, Dr. Matthew Walker describes how the different stages of sleep influence emotional and cardiovascular health.”
“These changes increase infection risk, weaken vaccine responses, and reduce early cancer surveillance. Yet immune aging is not fixed. Movement, sleep, stress regulation, temperature exposure, and nutrition shape immune cell balance and inflammatory activity over time.”