Related Episodes for What Five Days of High-Calorie Snack Overeating Did to Brain Insulin Signaling

Dr. Rhonda Patrick discusses nicotinamide riboside, biomarkers, belly fat loss, sex-specific health, curcumin & ashwagandha safety.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“In this podcast, we discuss and critically analyze a recent headline-grabbing editorial that was published in the Annals of Internal Medicine that reviewed three studies on the topic of multivitamins and chronic disease prevention. We analyze the important shortcomings of the studies and talk about the mechanism.”

“Whereas its link to diabetes is well known, what is likely underappreciated is that refined sugar may be linked to as many as 200,000 deaths worldwide each year from diabetes, cardiovascular disease, and cancer combined. Refined sugar also affects the brain.”

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“The main ingredient-interaction evidence concerns polyphenol oxidase. A small controlled crossover study found that a high-PPO banana smoothie greatly reduced circulating flavan-3-ol metabolites compared with a low-PPO berry drink or capsule control.”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“Satchin's work deals specifically with the timing of food and its relationship with our biological clocks, which are governed by a circadian rhythm. "Mice that ate within a 12-hour time period had 70% less fat and 28% less total body mass.".”

“Although the findings of a large meta-analysis published in the journal Annals of Internal Medicine indicated that there was no evidence to support the notion that consumption of saturated fat increased the risk of heart disease, the studies on which their conclusions were based were primarily observational.”

“People that used the sauna 2-3 times per week had a 20% lower risk of Alzheimer’s disease, and those that used the sauna 4-7 times per week had a 60% lower risk of Alzheimer's disease, compared to men that used the sauna 1 time per week.”