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Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Liberalizing the diet by altering protein, fat, and fiber intake may make the diet more tolerable. For those who have difficulty reaching and sustaining ketosis, ketone supplementation may be beneficial, but their use might interfere with weight loss.”

“In Part I of this three-part Aliquot series, creatine expert Dr. Darren Candow and I examine creatine through the lens of two critical systems—muscle and bone—and unpack how creatine supplementation affects muscle quality, physical function, and even skeletal health, particularly in older adults.”

“Eating a typical Western diet – high in processed foods and sugar-sweetened beverages – raises blood glucose and insulin levels, promotes inflammation, and contributes to many neurological disorders, including Alzheimer's disease.”

Dr. Rhonda Patrick discusses protein needs, choline in pregnancy, urolithin A, melatonin's benefits and risks, and creatine's effects on liver health.

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

“Mitochondrial health and overall health are intrinsically linked. Identifying ways to boost mitochondrial biogenesis – the formation of new mitochondria – ensures that cells maintain an adequate number of mitochondria to meet their energy needs.”

“But exercise — especially intense exercise — can also help to manage the symptoms once the disease develops. These Aliquot segments feature Dr. Giselle Petzinger, a board-certified neurologist who specializes in the care of patients with Parkinson's disease.”

“And one potential strategy for mitigating our risk for Alzheimer's disease as we age is a "cognoscopy" – a battery of assessments that measures some of the key biomarkers associated with the disease and can inform the trajectory of treatment.”

“Dr. Patrick and Wim talk a bit about Wim's back story that culminated in him trying out cold water immersion, the 2014 scientific publication of the “Wim Hof Method” which includes cold exposure during training, exposure to bacterial endotoxin, Wim's breathing techniques, and meditation.”