Search results for biomarkers

“Scientists have also identified interesting links between depression and obesity – likely mediated by elevated inflammation, since fat cells produce a wide array of inflammatory factors. In this Aliquot segment, psychiatrist Dr. Charles Raison describes the links between inflammation and depression.”

“Coordination of meal timing with the circadian rhythm can reduce markers of inflammation and affect aspects of metabolic health, including glucose regulation and insulin sensitivity. Animal studies suggest that overnight fasting induces autophagy.”

“As a prominent researcher and long-term follower of the ketogenic diet, Dr. D'Agostino believes that while someone can survive without fruits and vegetables, this dietary pattern may not be optimal for health.”

“She uses the omega-3 index, the percentage of EPA and DHA in red-blood-cell membranes, as a practical biomarker that reflects longer-term intake better than a single meal or supplement dose.”

“Peak plasma flavan-3-ol metabolites after the banana smoothie were 84 percent lower than after the capsule, while the low-PPO berry smoothie produced levels similar to the capsule. PPO is released when plant tissue is cut, bruised, or blended and can react with selected polyphenols before they reach circulation.”

“Among 2,315 middle-aged men followed for a median of 20.7 years, using a sauna four to seven times per week was associated with lower sudden cardiac death, cardiovascular mortality, and all-cause mortality than using one weekly session.”

“The mast cells release pro­inflammatory cytokines and proteases that damage the gut, leading to intestinal permeability, a condition otherwise known as “leaky gut.” This leakiness allows bacteria and bacterial antigens to cross the gut’s inner layer, the epithelium, and activate even more immune cells, leading to more inflammation – a key driver in the aging process.”

Dr. Rhonda Patrick reviews the evidence for nattokinase, how oat beta-glucans may aid with PFAS excretion, and HRT for APOE4 carriers.

“The Endocrine Society recommends aiming for testosterone concentrations in the mid-normal range while choosing an approved formulation based on patient preference, pharmacokinetics, formulation-specific effects, treatment burden, and cost.”

“In this member Q&A clip, Dr. Rhonda Patrick shares four practices she uses or finds compelling for healthy aging: sauna, sulforaphane-rich foods or supplements, time-restricted eating, and high-intensity interval training.”